Genetically Engineered Virus- Lawsuit

Discussion in 'Science and Technology' started by RodISHI, Mar 15, 2010.

  1. RodISHI
    Offline

    RodISHI Gold Member

    Joined:
    Nov 29, 2008
    Messages:
    10,392
    Thanks Received:
    1,858
    Trophy Points:
    280
    Ratings:
    +5,047
    Reprogramming Lentivirus: Human Klf4 provides an affordable method for......

    Allele Received Broad Patent on DNA-Expressed RNAi in China | AlleleBlog
    Nuclear reprogramming factor and induced pluripotent stem cells - Patent application
    CAUTION: All processes involving lentivirus should be performed in a safety

     
  2. eagleseven
    Offline

    eagleseven Quod Erat Demonstrandum

    Joined:
    Jul 8, 2009
    Messages:
    6,518
    Thanks Received:
    1,254
    Trophy Points:
    48
    Location:
    OH
    Ratings:
    +1,255
    Last edited: Mar 15, 2010
  3. CrusaderFrank
    Offline

    CrusaderFrank Diamond Member

    Joined:
    May 20, 2009
    Messages:
    81,170
    Thanks Received:
    14,903
    Trophy Points:
    2,210
    Ratings:
    +36,908
    The OP seems more like a Simpson's Episode
     
  4. Dr Gregg
    Offline

    Dr Gregg BANNED

    Joined:
    Jan 28, 2010
    Messages:
    2,901
    Thanks Received:
    198
    Trophy Points:
    0
    Ratings:
    +200
    Sounds like this worker was careless, as there are many steps to handle dangers laboratory reagents, especially live viruses. And if her colleague was at fault, then she is still careless to not notice carelessness of the coworker. many laboratories work with dangerious, live, infectious diseases, and they have no problems with infecting themselves. she's trying to blame the employer? Seems bogus to me, unless they didn't have safety regulation up to date, but I doubt that as these facilities have to work under Good Laboratory Practices (GLP) for their research and that requires frequent inspections.

    Plus, although the lentivirus is designed from HIV-1, its unable to replicate itself becasue its been mutated. THe lentivirus is often used in laboratory research to infect cells or animal tissue stably expressing the RNAi to knock down a gene of interest. It can infect a cell, and integrate into the geneome, but the virus itself can't be replicated, so the worst that can happen is the virus integrates into a cancer gene, and mutates it, but that is extremely rare. Even so, steps are taken to avoid infecting yourself.

    I've worked with lentivirus many times, I didn't infect myself. THis is a completely bogus lawsuit as the article hints at


    I know, its anothe rRodishi attempt to completely bastardize science. Maybe if you added arguments other than copy and pasting people would know what the hell you were trying to show here.

    oh, and here is another inconvenient fact to her case

     
    Last edited: Mar 15, 2010
  5. Dr Gregg
    Offline

    Dr Gregg BANNED

    Joined:
    Jan 28, 2010
    Messages:
    2,901
    Thanks Received:
    198
    Trophy Points:
    0
    Ratings:
    +200
    There have been 3 cases at my university where someone working with fully active HIV infected themselves, but its their own carelessness and not following safety protocols that lead to it
     
  6. thomas78
    Offline

    thomas78 Rookie

    Joined:
    Mar 21, 2010
    Messages:
    16
    Thanks Received:
    0
    Trophy Points:
    1
    Ratings:
    +0
    These stories keep getting published at least once every 2 or 3 years but more often than not, people forget about it and move on. I mean, it's not really probable that they were engineering it to hurt people though I guess the risk makes it dangerous enough.
     
  7. Dr Gregg
    Offline

    Dr Gregg BANNED

    Joined:
    Jan 28, 2010
    Messages:
    2,901
    Thanks Received:
    198
    Trophy Points:
    0
    Ratings:
    +200
    I work with lentivirus, its not dangerous unless you are completely careless. This case smells like a disgruntled employee trying gto stick it to their old company, as lentivirus can only infect you upon contact with the virus, and can't replicate, so worst case scenario it integrates into one cell in a gene that disrupts that gene function. VEry very rare case of that occuring, mostly it would integrate into junk DNA and have no effect. No way can it cause the problems she is stating.
     
    • Thank You! Thank You! x 1

Share This Page