Marty Makary Explains the Tylenol/Autism Concerns

[martybegan]

An article looking into what the FDA is actually saying about acetaminophen and pregnancy.

Marty Makary Explains the Tylenol/Autism Concerns

Bari Weiss sat down with FDA Chief Marty Makary to ask him a simple question: Why did the Department of Health and Human Services go public to warn women of this potential danger? Was it simple RFK, Jr. alarmism about autism, or is there a genuine concern?

Guess what? The evidence is not without ambiguity, but there are multiple studies suggesting a link between Tylenol use during pregnancy and autism in children.

There are a number of pathways involved in autism, each of which may be a cause. As we unlock the science behind these different pathways, we arrive at a point in our investigation where there is enough information that should be made available to the public in real time.

One finding that we believed rose to that level was the association between prenatal acetaminophen and autism—an association that was affirmed in a Harvard review published four weeks ago. One of the co-authors of the study, the dean of the Harvard T.H. Chan School of Public Health, said that there is a causal association between prenatal acetaminophen and the neurodevelopmental disorders of ADHD and autism spectrum disorder. When the dean of the Harvard School of Public Health is waving a flag in the air about an expanding epidemic that barely existed a generation ago, an epidemic that affects over two million kids in a way that makes their lives brutal, and we know that most acetaminophen prescribed is unnecessary, do you have a moral obligation to let the public know about this body of research?

If you look at the actual guidance, it recommends low doses and short durations, as the study data seems to show risks are when it's used for weeks on end.

 

[Marener]

Trump and RFK Jr are primarily marketers. This is all about making it look like they’re doing something.

They have a big splashy attention grabbing press conference.

In reality it’s a weak connection based on weak evidence resulting in a weak recommendation.

This will ultimately have little if any effect on autism.

But people see the theatre and they like it.

 

[martybegan]

Trump and RFK Jr are primarily marketers. This is all about making it look like they’re doing something.

They have a big splashy attention grabbing press conference.

In reality it’s a weak connection based on weak evidence resulting in a weak recommendation.

This will ultimately have little if any effect on autism.

But people see the theatre and they like it.

Its information being put out there.

And the article discusses what Marty Markay says about the issue, not Trump or RFKjr.

This guy.

Marty Makary - Wikipedia

He practices surgical oncology and gastrointestinal laparoscopic surgery at Johns Hopkins Hospital, is Mark Ravitch Chair in Gastrointestinal Surgery at Johns Hopkins School of Medicine, and is the chief of Islet Transplant Surgery at Johns Hopkins. Makary completed his surgical residency at Georgetown University and sub-specialty training in surgical oncology and gastrointestinal surgery at Johns Hopkins under John Cameron, later joining Cameron’s faculty practice.

Makary has pioneered advanced laparoscopic procedures, including the first laparoscopic Whipple and Frey’s procedures at Johns Hopkins, and led the development of “The Surgery Checklist” in collaboration with the World Health Organization. Makary has held several leadership roles at Johns Hopkins, including Credentials Chair, Director of Quality and Safety for Surgery, clinical lead for the Sibley Innovation Hub, and Executive Director of Improving Wisely. He has published extensively on surgical safety, frailty, teamwork, and hospital quality, and has advocated for public reporting of physician-endorsed quality measures, price transparency, and reform in drug pricing.

 

[Marener]

Its information being put out there.

And the article discusses what Marty Markay says about the issue, not Trump or RFKjr.

This guy.

Marty Makary - Wikipedia

The information already was out there. The press conference by Trump and RFK was embarrassing theatre.

It’s meant to give the impression of doing something meaningful.

 

[theHawk]

Trump and RFK Jr are primarily marketers. This is all about making it look like they’re doing something.

They have a big splashy attention grabbing press conference.

In reality it’s a weak connection based on weak evidence resulting in a weak recommendation.

This will ultimately have little if any effect on autism.

But people see the theatre and they like it.

Funny, the Canadian State media years ago warned people that pregnant women shouldn’t use Tylenol. Based on a study by the British backed by hundreds of scientists.




“But, but, but, I have to oppose everything Drumpf says!”

 

[martybegan]

The information already was out there. The press conference by Trump and RFK was embarrassing theatre.

It’s meant to give the impression of doing something meaningful.

The information was out there but not widely known.

Nothing is being banned, this is about guidance.

 

[Marener]

The information was out there but not widely known.

Nothing is being banned, this is about guidance.

It's been out there and discussed for years. It didn't get a lot of attention because the data is so weak and the connection is so weak.

This is about looking like they're doing something.

 

[martybegan]

It's been out there and discussed for years. It didn't get a lot of attention because the data is so weak and the connection is so weak.

This is about looking like they're doing something.

And yet the left reacts like the idiots they are.

This is about a government agency doing its job.

 

[Marener]

And yet the left reacts like the idiots they are.

This is about a government agency doing its job.

People don't take this government agency seriously anymore.

 

[martybegan]

People don't take this government agency seriously anymore.

Lefties don't take reality seriously anymore.

 

[Moonglow]

Harvard dean was paid $150K for testimony in suit ...​

Scripps News
https://www.scrippsnews.com › health › scientist-behind...




2 days ago — Scientist behind autism study cited by Trump admin paid $150K by plaintiffs suing Tylenol manufacturer. Dr. Andrea Baccarelli's expert testimony .

 

[Marener]

Lefties don't take reality seriously anymore.

RFK Jr and Trump have little connection with reality.

 

[Crepitus]

An article looking into what the FDA is actually saying about acetaminophen and pregnancy.

Marty Makary Explains the Tylenol/Autism Concerns





If you look at the actual guidance, it recommends low doses and short durations, as the study data seems to show risks are when it's used for weeks on end.

 

[martybegan]

View attachment 1166426

As usual no response to the actual article.

 

[Foxfyre]

An article looking into what the FDA is actually saying about acetaminophen and pregnancy.

Marty Makary Explains the Tylenol/Autism Concerns





If you look at the actual guidance, it recommends low doses and short durations, as the study data seems to show risks are when it's used for weeks on end.

The more I've looked into this, the more I think President Trump's remarks are not without justification. Something is causing an alarming increase in autism and we need to know what it is.

A link between autism and Tylenol/acetaminophen seems to exist, however ambiguous at this point, and that merits a lot more intensive research. We are likely to find that mysterious autism trigger probably in the least suspected place(s).

Now I wish President Trump has been a bit less 'off the top of his head/thinking out loud' about it, but that's usually not his style. I wish he had said that we are looking at a possible Tylenol link and autism and, while the evidence is not yet 100% conclusive, there does seem to be cause for concern re taking Tylenol while pregnant. There is no evidence Tylenol is a problem for most people. I think pregnant women would be wise to consult their physicians before taking the drug.

The NIH position on this (emphasis mine)

". . .This paper has reviewed the possible contribution of acetaminophen to the development of autism and ADHD. Much research has already been devoted to this topic, including a multitude of longitudinal studies and murine models. Nonetheless, this review expands on a theoretical framework of acetaminophen-induced ASD and ADHD grounded in a bioenergetics perspective. Upon evaluating NAPQI’s potency against mitochondria as well as the mitochondrial abnormalities present in these disorders, we recommend reviewing maternal usage of acetaminophen. . . "

Acetaminophen’s Role in Autism and ADHD: A Mitochondrial Perspective - PMC

One in 36 children were identified with autism in 2020, a 22% increase from 2018 and a 98% increase from 2010. Simultaneously, attention-deficit/hyperactivity disorder (ADHD) diagnoses increased 36% from 2003 to 2016–2019. Despite this surge, their ...

pmc.ncbi.nlm.nih.gov

Meanwhile acetaminophen is a godsend for people like me who need frequent painkillers but don't want to take narcotics and can't take NSAIDS. I will continue to take Tylenol/acetaminophen without fear. But then should I become pregnant at my age, it would be a miracle exceeding Biblical proportions.