Sanger's writings echoed ideas about inferiority and loose morals of particular races that were widespread in the contemporary United States. In one "What Every Girl Should Know" commentary, she observed that Aboriginal Australians were "just a step higher than the chimpanzee" with "little sexual control," as compared to the "normal man and Woman."[85]
Such attitudes did not keep her from collaborating with African-American leaders and professionals who saw a need for birth control in their communities. In 1929, James H. Hubert, a black social worker and leader of New York's Urban League, asked Sanger to open a clinic in Harlem.[86] Sanger secured funding from the Julius Rosenwald Fund and opened the clinic, staffed with black doctors, in 1930. The clinic was directed by a 15-member advisory board consisting of black doctors, nurses, clergy, journalists, and social workers. The clinic was publicized in the African-American press and in black churches, and it received the approval of W. E. B. Du Bois, founder of the NAACP.[87] She did not tolerate bigotry among her staff, nor would she tolerate any refusal to work within interracial projects.[88] Sanger's work with minorities earned praise from Martin Luther King, Jr., in his 1966 acceptance speech for the Margaret Sanger award.[89]
From 1939 to 1942 Sanger was an honorary delegate of the Birth Control Federation of America, which included a supervisory role — alongside Mary Lasker and Clarence Gamble — in the Negro Project, an effort to deliver birth control to poor black people.[90] Sanger wanted the Negro Project to include black ministers in leadership roles, but other supervisors did not. To emphasize the benefits of involving black community leaders, she wrote to Gamble "we do not want word to go out that we want to exterminate the Negro population and the minister is the man who can straighten out that idea if it ever occurs to any of their more rebellious members." This quote has been cited by Angela Davis to support her claims that Sanger wanted to exterminate black people.[91] However, New York University's Margaret Sanger Papers Project, argues that in writing that letter, "Sanger recognized that elements within the black community might mistakenly associate the Negro Project with racist sterilization campaigns in the Jim Crow South, unless clergy and other community leaders spread the word that the Project had a humanitarian aim."[92]