Superbug Resistant to All Antibiotics Has Killed a Woman in the US

[Weatherman2020]

The lefts attack on the pharmaceutical industry is reaping results. No ne wants to invest tens of millions of dollars in the slim chance they can sell the drug ten years from now and still get sued because one in a million has an allergic reaction.

A superbug resistant to every available antibiotic has killed a woman in the US.

But don’t worry, the government’s on it: “Many major pharmaceutical companies have stopped developing new antibiotics altogether. Last year for example, the FDA turned down Cempra Pharmaceuticals‘ new antibiotic, a drug designed to fight a type of bacterial pneumonia called solithromycin, citing too little information on how the drug might impact the liver. That additional trial would require testing out the antibiotic on 9,000 people.”


FYI: If aspirin were invented today it would not get FDA approval the restrictions are so high. Yeah, heart attack and cancer preventing aspirin would not be available.

 

[2aguy]

God is here for us......

The Science World Is Freaking Out Over This 25-Year-Old's Answer to Antibiotic Resistance

But Shu Lam, a 25-year-old PhD student at the University of Melbourne in Australia, has developed a star-shaped polymer that can kill six different superbug strains without antibiotics, simply by ripping apart their cell walls.

"We’ve discovered that [the polymers] actually target the bacteria and kill it in multiple ways," Lam told Nicola Smith from The Telegraph. "One method is by physically disrupting or breaking apart the cell wall of the bacteria. This creates a lot of stress on the bacteria and causes it to start killing itself."

The research has been published in Nature Microbiology, and according to Smith, it's already being hailed by scientists in the field as "a breakthrough that could change the face of modern medicine".

Before we get too carried away, it's still very early days. So far, Lam has only tested her star-shaped polymers on six strains of drug-resistant bacteria in the lab, and on one superbug in live mice.

But in all experiments, they've been able to kill their targeted bacteria - and generation after generation don't seem to develop resistance to the polymers.

The polymers - which they call SNAPPs, or structurally nanoengineered antimicrobial peptide polymers - work by directly attacking, penetrating, and then destabilising the cell membrane of bacteria.

Unlike antibiotics, which 'poison' bacteria, and can also affect healthy cells in the area, the SNAPPs that Lam has designed are so large that they don't seem to affect healthy cells at all.

"With this polymerised peptide we are talking the difference in scale between a mouse and an elephant," Lam's supervisor, Greg Qiao, told Marcus Strom from the Sydney Morning Herald. "The large peptide molecules can't enter the [healthy] cells."

You can see the SNAPPs (green) surrounding and ripping apart bacterial cells below:

 

[JakeStarkey]

weatherman creates a hasty generalization highlighted by an unexpected quote from the link: "the FDA turned down Cempra Pharmaceuticals‘ new antibiotic, a drug designed to fight a type of bacterial pneumonia called solithromycin, citing too little information on how the drug might impact the liver."

What about effects on the liver?

 

[RodISHI]

Sorry but the attack on the Pharm industry has been earned by them for pushing off crap that does a lot more damage than it helps. When they got FDA going after natural foods and cures that have been known for thousands of years and keeping pharmaceuticals that they have known for years does extreme damage the industry screwed its self.

 

[badger2]

We would question the diatomaceous earth approach of the polymer. The organism supposedly reported was Klebsiella, and it came from India. So too did the military strain of smallpox and the ochagovostíu (focus) of Cholera is also India.

 

[badger2]

What is the method of delivery for these polymers that supposedly target only Klebsiella and leave everything else alone?