US Patent for Coronavirus (Patent # 10,130,701)

[keepitreal]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

 

[bluzman61]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

Let's keep our fingers crossed on this one.

 

[depotoo]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

That is not for corona virus we are dealing with which is covid-19. This was a vaccine for the avian flu/ corona virus. From 2015

 

[ReinyDays]

Thank goodness ... I was worried about my guinea fowl ...

 

[keepitreal]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

That is not for corona virus we are dealing with which is covid-19. This was a vaccine for the avian flu/ corona virus. From 2015

First of all, read the other thread I started
then tell me how you know what we're dealing with.

I believe we are actually dealing with AI H7N9

Did you know WHO 'named' it covid-19
and is being scrutinized?


SARS-CoV-2 is an appropriate name for the new coronavirus

 

[Denizen]

The year of the patent is 2015, so the coronavirus has been known for some time.

Pirbright was also studying Swine fever, SARS and MERS. Who knows what else they are studying?

Could the coronavirus have transmitted from a research lab?

Pirbright’s livestock coronavirus research – your questions answered | The Pirbright Institute

... The Institute holds Patent no. 10130701 which covers the development of an attenuated (weakened) form of the coronavirus that could potentially be used as a vaccine to prevent respiratory diseases in birds and other animals. Many vaccines are made in this way, from flu to polio. We have not yet developed an IBV vaccine, but research is ongoing.

The Institute is strategically funded by the Biotechnology and Biological Sciences Research Council, part of UK Research and Innovation (BBSRC UKRI) and also receives funding from many other organisations including the Bill & Melinda Gates Foundation. The patented work was not funded by the Bill & Melinda Gates Foundation. More information on The Livestock Antibody Hub which is funded by the Bill & Melinda Gates Foundation is available on our website.

The coronavirus first identified in Wuhan, China, earlier this year is a new coronavirus, the seventh coronavirus identified that is able to infect humans. Six other coronaviruses are capable of infecting humans and these can cause diseases which range from mild to severe, and include the common cold, severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS). The exact origin of the new virus is unknown but initial confirmation shared by China and the World Health Organization (WHO) indicates that this new virus is genetically similar to a SARS-like coronavirus found in bats. The source of the outbreak has yet to be confirmed and investigations are ongoing. ...

 

[Care4all]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

That is not for corona virus we are dealing with which is covid-19. This was a vaccine for the avian flu/ corona virus. From 2015

First of all, read the other thread I started
then tell me how you know what we're dealing with.

I believe we are actually dealing with AI H7N9

Did you know WHO 'named' it covid-19
and is being scrutinized?


SARS-CoV-2 is an appropriate name for the new coronavirus

interesting! So this is a SARS Corona Virus variant? or mutation?

whatever.... the name should be the same for micro biologists/scientists and the public imo...

 

[keepitreal]

FIELD OF THE INVENTION

The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease.

BACKGROUND TO THE INVENTION
Avian infectious bronchitis virus (IBV), the aetiological agent of infectious bronchitis (IB), is a highly infectious and contagious pathogen of domestic fowl that replicates primarily in the respiratory tract but also in epithelial cells of the gut, kidney and oviduct. IBV is a member of the Order Nidovirales, Family Coronaviridae, Subfamily Corona virinae and Genus Gammacoronavirus; genetically very similar coronaviruses cause disease in turkeys, guinea fowl and pheasants.

US Patent for Coronavirus (Patent # 10,130,701)

That is not for corona virus we are dealing with which is covid-19. This was a vaccine for the avian flu/ corona virus. From 2015

First of all, read the other thread I started
then tell me how you know what we're dealing with.

I believe we are actually dealing with AI H7N9

Did you know WHO 'named' it covid-19
and is being scrutinized?


SARS-CoV-2 is an appropriate name for the new coronavirus

interesting! So this is a SARS Corona Virus variant? or mutation?

whatever.... the name should be the same for micro biologists/scientists and the public imo...

I think it is a mutation of AI H7N9,
I started another thread regarding this

What about this Dispatch from the CDC in Nov. 2019

Clinical REsearch During Outbreaks (CREDO) Training for Low- and Middle-Income Countries

And, look at the address in your address bar