- Nov 29, 2008
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They call it off shelf use when used or tried for various diseases but it is still used and medical education doesn't always include the history disasters from use of certain pharmaceuticals.
Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet’s disease, apththous ulcers in HIV patients, and prurigo nodularis. Behçet’s Disease treated with thalidomide - Google Search
www.intechopen.com
www.webmd.com
Bacterial and viral infections should be treated with anti-bacterial an anti-viral agents.
The drug does not kill the bacteria that cause leprosy, but it does change the body's immunological response to those bacteria. Thalidomide can decrease the level of TNF-α (tumour necrosis factor alpha) in ENL patients. TNF-α is responsible for the tissue inflammation in ENL patients.
Successful long-term thalidomide therapy for discoid lupus erythematosus-lichen planus overlap syndrome
Author(s): Zhang, Lisa; Au, Sonoa; Aronson, Iris K | Abstract: Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet’s disease...
escholarship.org
Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet’s disease, apththous ulcers in HIV patients, and prurigo nodularis. Behçet’s Disease treated with thalidomide - Google Search
Infectious Agents in Etiopathogenesis of Behçetâs Disease
Behçet disease (BD) is a chronic, relapsing, multisystemic vasculitis with unknown etiopathogenesis. It is widely accepted that an altered immune response triggered by an infectious agent or by an otoantigen in a genetically predisposed individual plays major role in the pathogenesis of BD. In...
www.intechopen.com
Thalidomide Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD
Find patient medical information for thalidomide oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.
www.webmd.com
Bacterial and viral infections should be treated with anti-bacterial an anti-viral agents.
The drug does not kill the bacteria that cause leprosy, but it does change the body's immunological response to those bacteria. Thalidomide can decrease the level of TNF-α (tumour necrosis factor alpha) in ENL patients. TNF-α is responsible for the tissue inflammation in ENL patients.
