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It begins: FDA may pull Avastin approval over cost concerns
When Barack Obama and the Democrats spent most of a year pushing their deeply unpopular health-care system overhaul, they repeatedly insisted that government intervention in the market would not mean that treatment decisions would come down to cost issues even while demonizing providers as Tonsil Vultures and amputation-happy predators. Today, however, the Washington Post reports on an effort at the FDA to decertify Avastin as a treatment for breast cancer and its implications for cost savings at Medicare:
Federal regulators are considering taking the highly unusual step of rescinding approval of a drug that patients with advanced breast cancer turn to as a last-ditch hope.
The debate over Avastin, prescribed to about 17,500 women with breast cancer a year, has become entangled in the politically explosive struggle over medical spending and effectiveness that flared during the battle over health-care reform: How should the government balance protecting patients and controlling costs without restricting access to cutting-edge, and often costly, treatments?
Avastin received accelerated approval from the FDA for metastatic breast cancer in 2008 on the basis of a study in which patients who were treated with Avastin, in combination with paclitaxel, had a progression-free survival advantage of 5.5 months over paclitaxel alone but no overall survival advantage.3 Toxic effects were substantial, but this interim end point suggested real clinical benefit. Unfortunately, in what were supposed to be confirmatory studies enrolling almost 2000 women, progression-free survival was shorter than in the initial study, and no quality-of-life or survival advantage could be shown for Avastin-containing regimens.
The Avastin Story
Avastin received accelerated approval from the FDA for metastatic breast cancer in 2008 on the basis of a study in which patients who were treated with Avastin, in combination with paclitaxel, had a progression-free survival advantage of 5.5 months over paclitaxel alone but no overall survival advantage.3 Toxic effects were substantial, but this interim end point suggested real clinical benefit. Unfortunately, in what were supposed to be confirmatory studies enrolling almost 2000 women, progression-free survival was shorter than in the initial study, and no quality-of-life or survival advantage could be shown for Avastin-containing regimens.
When you count your life by days two months can be a Godsend.but it will keep your cancer from worsening by an average of 1 to 2 months.”
The Avastin Story
Avastin received accelerated approval from the FDA for metastatic breast cancer in 2008 on the basis of a study in which patients who were treated with Avastin, in combination with paclitaxel, had a progression-free survival advantage of 5.5 months over paclitaxel alone but no overall survival advantage.3 Toxic effects were substantial, but this interim end point suggested real clinical benefit. Unfortunately, in what were supposed to be confirmatory studies enrolling almost 2000 women, progression-free survival was shorter than in the initial study, and no quality-of-life or survival advantage could be shown for Avastin-containing regimens.
Here's what you leave out!
When you count your life by days two months can be a Godsend.but it will keep your cancer from worsening by an average of 1 to 2 months.
I know. My father was given THREE WEEKS TO LIVE.
No, he did not have breast cancer (of course, BUT HE DID HAVE CANCER), and the measures they took to extend my father's life by THREE MONTHS was everything to us.
But liberals like Obama will say "take a pain pill because YOUR LIFE doesn't justify the cost."
THE REAL WAR ON WOMEN IS BY THE LEFT!
No, he did not have breast cancer (of course, BUT HE DID HAVE CANCER), and the measures they took to extend my father's life by THREE MONTHS was everything to us.
Thanks.
Avastin shows everything that was kind of wrong with the system, where profit was put above science.
the sad thing is, the GOP is all about profit.
Fuking hypocrite.
Bitch and moan about Obama's preventative health ideas that give a better quality of life with less costs then bitch because an end of life drug that has issues and is to expensive is questioned.
What the hell you want to happen. You know how much money is wasted trying to extend a dying patients life by a few days or weeks.
There has to be a limit on how much is spent to prolong life a few days or even weeks.
We are all gonna die. Bankrupting the health system for a few days is stupid. I watched it happen with a MIL. Spent hundreds of thousands of dollars to do what? Postpone the inevitiable by a week. And she didn't even know it was being done to her. Stupid.
Fuking hypocrite.
Bitch and moan about Obama's preventative health ideas that give a better quality of life with less costs then bitch because an end of life drug that has issues and is to expensive is questioned.
What the hell you want to happen. You know how much money is wasted trying to extend a dying patients life by a few days or weeks.
There has to be a limit on how much is spent to prolong life a few days or even weeks.
We are all gonna die. Bankrupting the health system for a few days is stupid. I watched it happen with a MIL. Spent hundreds of thousands of dollars to do what? Postpone the inevitiable by a week. And she didn't even know it was being done to her. Stupid.
Here's what you leave out!
When you count your life by days two months can be a Godsend.but it will keep your cancer from worsening by an average of 1 to 2 months.
I know. My father was given THREE WEEKS TO LIVE.
No, he did not have breast cancer (of course, BUT HE DID HAVE CANCER), and the measures they took to extend my father's life by THREE MONTHS was everything to us.
But liberals like Obama will say "take a pain pill because YOUR LIFE doesn't justify the cost."
THE REAL WAR ON WOMEN IS BY THE LEFT!
Actually men can get breast cancer....
Male Breast Cancer Statistics, Symptoms, Signs, Facts, Causes and Treatment by MedicineNet.com
I agree with you...to families any amount of time that can add to their loved ones lives is important to them. I guess Obama doesn't care about his loved ones either...i wonder what he'd think if Michelle needed it?
No, he did not have breast cancer (of course, BUT HE DID HAVE CANCER), and the measures they took to extend my father's life by THREE MONTHS was everything to us.
Avastin doesn't extend your life if you're a breast cancer patient, not even the original trials upon which accelerated FDA approval was judged warranted claimed that.
but it will keep your cancer from worsening by an average of 1 to 2 months.”[/quote]
http://www.nejm.org/doi/full/10.1056/NEJMc1109550
Fuking hypocrite.
Bitch and moan about Obama's preventative health ideas that give a better quality of life with less costs then bitch because an end of life drug that has issues and is to expensive is questioned.
What the hell you want to happen. You know how much money is wasted trying to extend a dying patients life by a few days or weeks.
There has to be a limit on how much is spent to prolong life a few days or even weeks.
We are all gonna die. Bankrupting the health system for a few days is stupid. I watched it happen with a MIL. Spent hundreds of thousands of dollars to do what? Postpone the inevitiable by a week. And she didn't even know it was being done to her. Stupid.
What a fine example of the implied high road taken by the Left when engaging in what they believe passes for civil discourse.
Without vulgar language your repertoire would be...what? ....cut in half?
Notice how the Liberal replaces intellect with emotion. This is, no doubt, based on a medieval concept of recognizing witches and demons. In fact, Liberals attempt to deal with opponents in similar fashion: recall Clarence Thomas High Tech Lynching.
I look forward to the next post in which you prove that you have reached the nadir of your ability.
Fuking hypocrite.
Bitch and moan about Obama's preventative health ideas that give a better quality of life with less costs then bitch because an end of life drug that has issues and is to expensive is questioned.
What the hell you want to happen. You know how much money is wasted trying to extend a dying patients life by a few days or weeks.
There has to be a limit on how much is spent to prolong life a few days or even weeks.
We are all gonna die. Bankrupting the health system for a few days is stupid. I watched it happen with a MIL. Spent hundreds of thousands of dollars to do what? Postpone the inevitiable by a week. And she didn't even know it was being done to her. Stupid.
What a fine example of the implied high road taken by the Left when engaging in what they believe passes for civil discourse.
Without vulgar language your repertoire would be...what? ....cut in half?
Notice how the Liberal replaces intellect with emotion. This is, no doubt, based on a medieval concept of recognizing witches and demons. In fact, Liberals attempt to deal with opponents in similar fashion: recall Clarence Thomas High Tech Lynching.
I look forward to the next post in which you prove that you have reached the nadir of your ability.
And you can basically boil it down to "screw the old, let 'em die!"
What a fine example of the implied high road taken by the Left when engaging in what they believe passes for civil discourse.
Without vulgar language your repertoire would be...what? ....cut in half?
Notice how the Liberal replaces intellect with emotion. This is, no doubt, based on a medieval concept of recognizing witches and demons. In fact, Liberals attempt to deal with opponents in similar fashion: recall Clarence Thomas High Tech Lynching.
I look forward to the next post in which you prove that you have reached the nadir of your ability.
And you can basically boil it down to "screw the old, let 'em die!"
Liberals are simply sheep lined up for slaughter and will fight you to remain in line.
So Obama cuts costs and you complain...maybe you should just get your own medication and stop relying on Obama.
So Obama cuts costs and you complain...maybe you should just get your own medication and stop relying on Obama.
