Researchers Have Found a Way to Delay Aging

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Mar 16, 2010
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Researchers Have Found a Way to Delay Aging


More and more, scientists are becoming convinced that aging is a disease that can be stopped or, at least, slowed. Recently, researchers from Russia and Sweden investigated this idea further in a joint study by Lomonosov Moscow State University and Stockholm University. Their study, published in the journal Aging, focuses on the role of mitochondria in the aging of organisms.


Under the leadership of renowned Russian biologist Vladimir Skulachev, the researchers experimented with a special strain of genetically-modified mice. A single mutation was introduced into the genome of these mice, which were created and characterized in Sweden. This mutation substantially accelerated mitochondrial mutagenesis. Instead of living more than two years, these mutated mice lived less than a year, and developed many age-related diseases and defects — clearly indicating that these were caused by aging.

The researchers treated a group of 100-day-old genetically modified mice with a synthetic compound called SkQ1, an artificial antioxidant that targets the mitochondria. SkQ1 was developed in Moscow State University in Skulachev’s lab. The SkQ1 was added into the drinking water of these mice, while a separate control group were given pure water. By the time the mice aged 200-250 days, the control group had aged rapidly and lost weight, experienced a decrease in body weight and temperature, had osteoporosis, and were developing alopecia. There was also a decrease in mobility and oxygen intake — all signs of aging. On the other hand, these traits were dramatically decelerated for the mice treated with SkQ1.

With these promising results, Skulachev is already working on developing potential drug treatments based on SkQ1. One is an eye drop called Visomitin, which has already been approved in Russia and has passed phase 2 clinical trials in the U.S. Another project currently in development is an oral version of SkQ1. In Russia, this drug is now on clinical trials. If all goes well and as expected, the drug can be approved for public use within 2-3 years.

Hold on to your trousers, according to the study paper, mice treated with SkQ1 lived an average 335 days versus 290 days for untreated mice. That's a 15.5% increase in lifespan; it's like increasing human life expectancy from 80 to 92.4 (assuming the results actually translate to humans). Actually, damn, that's pretty impressive.

The fact that we can actually slow down aging in 2017 to the point of adding another decade to life expectancy, isn't too shabby at all; things can only get better, right?
 
The Russians are hacking our bodies :eek:
Pence will hold them accountable! Sanctions! Sanctions! Sanctions!
Yes, the new meds will not allowed to be shipped to western countries according to their own sanctions. What a pity!
 
Any advance in a healthy longevity is a benefit to mankind. Ernt Mayr wrote his last book at 98 years old. He was one of the great evolutionary biologists of the 20th Century. We all would have gained had he had another 20 years of productive life.

As someone 73 years old, I have come to realize that in the first 100 years of life, most of us are just getting a handle on how things work. Anything that would extend a productive lifespan is a good thing.
 
I can help people increase their life span from 80 to 90 + years with this simple solution advice.
Break all ties with your
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Lol...Are you speaking from experience Michael...Anyways..I believe a university in North Carolina found the gene that may cause aging in the late 1990's but I have not heard anything further on that subject since meaning nothing else was found or they have found something significant and are not letting on..The other thing I would like to point out is there is a jellyfish called the immortal jellyfish .. It is different from all the other jellyfish and it has the ability to reverse its age from aged to young at will... If we can find the process that these jellyfish use or splice that ability into our own genes then we could also technically live long long extended lives.. there are other examples of increasing the life expectancies and some are very promising to say the least...
 

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