Israel Artificial Pancreas Breakthrough

JStone

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Warren Buffett: "If you go to the Middle East looking for oil, you don't need to stop in Israel. But, if you're looking for brains, for energy, for integrity, for imagination, it's the only stop you need to make"

http://asweetlife.org/a-sweet-life-...ideo-the-artificial-pancreas-in-action/21243/

Israeli-Developed 'Artificial Pancreas’ Tested
Apparently for the first time in the world, a recent research study on children with type 1 (insulin-dependent, juvenile- onset) diabetes aimed at creating an effective artificial pancreas to produce insulin was held not in a hospital but in a hotel.

The clinical trial was conducted by specialists at the Schneider Children’s Medical Center (SCMC) at the Kibbutz Ma’aleh Hahamisha Hotel outside Jerusalem. The prospective, crossover study, in which the whole group receive the treatment but at different times, was part of the three-day DREAM (Diabetes wireless Artificial pancreas consortium) Camp for Children with Diabetes.

It consisted of 18 kids aged 12 to 15 years; nine of them were were connected to the artificial pancreas system on the first night of the camp, while eight were connected on the second night. The benefit of being in a hotel rather than a hospital ward was that the more pleasant, non-threatening environment made the results more accurate.

The MD-Logic Artificial Pancreas, developed at the SCMS’s Institute for Endocrinology and Diabetes, consists of an off-the-shelf subcutaneous glucose sensor that monitors glucose levels, and an insulin pump. The sensor and pump are connected to a computer that programs the information and stipulates the amount of insulin that should be released to the body in order to maintain blood glucose balance.

This innovation “closes the loop” between the sensor and the pump and relieves the patients with diabetes from the daily burden of dealing with their diabetes and has the potential to significantly improve the quality of life of patients with diabetes.

The experimental artificial pancreas is aimed at providing a real solution for patients with type 1 diabetes, which usually begins in early childhood. The research is being carried out at the Shaffer Institute for Endocrinology and Diabetes at the Petah Tikva hospital’s National Center of Childhood Diabetes. The project is headed by institute director Prof. Moshe Phillip and Dr. Revital.

Following the successful trial, Phillip said: “I am proud to head and be a part of the pioneering team working for a number of years to find a technological solution that will significantly improve the lives of millions of diabetics around the world. The MD-Logic Artificial Pancreas and the DREAM Projects will enable patients to be relieved of the continuous need to check glucose levels and inject insulin, while ensuring long-term balance which significantly reduces the chance of complications from diabetes. The entire staff in the Institute is excited to be part of this important historic project.”

“This is a significant landmark in research,” he added. “This is, to the best of our knowledge, the first time in the world that such a trial project has been taken outside the hospital, illustrating a normal life for youngsters with diabetes, while using an automatic insulin delivery system during the night.” The overall success of the research represents genuine good news to millions of patients with diabetes in Israel and the world, he said.

Con't: Israeli-developed 'artificial pancrea... JPost - Health & Science
 
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Medical advances from the Arabs and Muslimes?


 
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Israeli Pharmaceutical Company Tests Groundbreaking New Cancer Vaccine

[ame=http://www.youtube.com/watch?v=XhEwj6Ue13s]Vaxil BioTherapeutic - YouTube[/ame]

Islime: "We Desire Death Like You Desire Life"
[ame=http://www.youtube.com/watch?v=CWIDZ7Jpdqg]Hamas - "We desire death like you desire life" - YouTube[/ame]
 
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Israel, Artificial Nation Breakthrough

John 12:13 They took palm branches and went out to meet him, shouting, “Hosanna! “Blessed is he who comes in the name of the Lord! “Blessed is the king of Israel!”

John 1:49 Then Nathanael declared, "Rabbi, you are the Son of God; you are the King of Israel."

Pulitzer Prize-Winning Writer Charles Krauthammer...
Israel is the very embodiment of Jewish continuity: It is the only nation on earth that inhabits the same land, bears the same name, speaks the same language, and worships the same God that it did 3,000 years ago. You dig the soil and you find pottery from Davidic times, coins from Bar Kokhba, and 2,000-year-old scrolls written in a script remarkably like the one that today advertises ice cream at the corner candy store.

Harvard Semitic Museum: The Houses of Ancient Israel
In archaeological terms The Houses of Ancient Israel: Domestic, Royal, Divine focuses on the Iron Age (1200-586 B.C.E.). Iron I (1200-1000 B.C.E.) represents the premonarchical period. Iron II (1000-586 B.C.E.) was the time of kings. Uniting the tribal coalitions of Israel and Judah in the tenth century B.C.E., David and Solomon ruled over an expanding realm. After Solomon's death (c. 930 B.C.E.) Israel and Judah separated into two kingdoms.
Israel was led at times by strong kings, Omri and Ahab in the ninth century B.C.E. and Jereboam II in the eighth. The Houses of Ancient Israel § Semitic Museum

Harvard University Semitic Museum: Jerusalem during the reign of King Hezekiah--New exhibition at the Semitic Museum re-creates numerous aspects of ancient Israel
The Semitic Museum has installed a new exhibition that brings the world of biblical Israel into vivid, three-dimensional reality. "The Houses of Ancient Israel: Domestic, Royal, Divine" immerses the viewer in Israelite daily life around the time of King Hezekiah (8th century B.C.), creating an experiential environment based on the latest archaeological, textual, and historical research.
The centerpiece of the exhibition is a full-scale Israelite house, open on one side, filled with authentic ancient artifacts that show how life was lived by common inhabitants of ancient Jerusalem. Agricultural tools, a cooking area, and a stall occupied by a single, scruffy ram fill the ground floor of the cube-shaped, mud-brick structure, which, thankfully, is not olfactorily authentic. The upper story, reached by a ladder, is devoted to eating and sleeping. Harvard Gazette: Jerusalem during the reign of King Hezekiah

Yale University Press: The Archaeology of Ancient Israel
In this lavishly illustrated book some of Israel's foremost archaeologists present a thorough, up-to-date, and readily accessible survey of early life in the land of the Bible, from the Neolithic era (eighth millennium B.C.E.) to the fall of Jerusalem and the destruction of the First Temple in 586 B.C.E. It will be a delightful and informative resource for anyone who has ever wanted to know more about the religious, scientific, or historical background of the region.

The Archaeology of Ancient Israel - Ben-Tor, Amnon; Greenberg, R. - Yale University Press

PBS Nova ...
In the banks of the Nile in southern Egypt in 1896, British archaeologisit Flinders Petrie unearthed one of the most important discoveries in biblical archaeology known as the Merneptah Stele. Merneptah's stele announces the entrance on the world stage of a People named Israel.

The Merneptah Stele is powerful evidence that a People called the Israelites are living in Canaan over 3000 years ago

Dr. Donald Redford, Egyptologist and archaeologist: The Merneptah Stele is priceless evidence for the presence of an ethnical group called Israel in Canaan.
[ame=http://www.youtube.com/watch?v=Yvg2EZAEw5c]1/13 The Bible's Buried Secrets (NOVA PBS) - YouTube[/ame]
 
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Israel, Artificial Nation Breakthrough

Fakestinians :lol:

Former PLO Leader Zuheir Mohsen :lol:
The Palestinian people does not exist. The creation of a Palestinian state is only a means for continuing our struggle against the state of Israel for our Arab unity. In reality today there is no difference between Jordanians, Palestinians, Syrians and Lebanese. Only for political and tactical reasons do we speak today about the existence of a Palestinian people, since Arab national interests demand that we posit the existence of a distinct Palestinian people to oppose Zionism.
Zuheir Mohsen - Wikipedia, the free encyclopedia

Shaykh Prof. Abdul Hadi Palazzi, Italian Muslim Assembly :lol:
I believe that "Palestinian identity" is something completely artificial: it was forged as a propagandistic tool against Israel. The strange fact is that, at least here in Europe, I have never heard an Arab from the Land of Israel ("Palestine") say: "I am Palestinian."

Please remember that the so-called hero of "Palestinian independence," the pro-Nazi Grand Mufti of British Mandate Palestine, Haj Amin al-Husseini, never claimed that "Palestinians" are to be an independent people: all of his official declarations state that "Palestine must be recognized as a integral part of Syria."
ISRAEL SHOULD DECLARE OSLO NULL AND VOID (Prof. Abdul Hadi Palazzi August, 1998

Guy Milliere, Eminent Professor of History and Political Science, University of Paris :lol:
No one had heard of a Palestinian people before the mid-1960s. They did not exist. Israel under the British Mandate until Israel' s Independence in 1948 was called Palestine. All Jews who were born there until i948 had the word « Palestine » stamped on their passports. The current Palestinians are those Arabs who, for a variety of reasons, decided to leave the land during the 1947 War of Independence, when five countries--Jordan, Egypt, Syria, Lebanon and Iraq--attacked the 600,000 people in the fledgling state of Israel the day after its birth, hoping to kill it in the crib.
The War Against Israel Goes On- by Guy Millière | dreuz.info

Fakestinian History :lol:

Historian Sir Martin Gilbert, Author of 10 Books on Jewish and Middle East History :lol:
On August 18 Yasir Arafat, speaking as head of the Palestinian National Authority in Gaza and Jericho, told Arab youngsters at a summer camp, "Those of you who lit the intifada fire must now act as defenders of this young state, whose capital is Jerusalem. It is Bir Salem [the fountain of Salem]. Salem was one of the Canaanite Kings, one of our forefathers. This city is the capital of our children and our children's children. If not for this belief and conviction of the Palestinian nation, this people would have been erased from the face of the earth, as were so many other nations."

King Salem is a newcomer on the historical scene. No such Canaanite, Jebusite or Philistine king is known to history

Fakestinian Messiahs. Did you know Jesus Christ, the Jewish rabbi who taught from the Torah and observed Passover in the Jerusalem Temple, was REALLY a muslime fakestinian? :lol:

[ame=http://www.youtube.com/watch?v=lWLyVU0Otlk]Arafat said Jesus was a Palestinian. Palestinian author and TV host agree. - YouTube[/ame]

:clap2:
We’re talking about an ongoing chain [of prophets of the Islam], from Adam to Muhammad. It’s an ongoing chain, representing the call for monotheism, and the mission of Islam… The prophets were all of the same religion [Islam]… Jesus was born in this land. He lived in this land. It is known that he was born in Bethlehem… He also lived in Nazereth, moved to Jerusalem. So he was a Palestinian par excellence…We respect Jesus, we believe in him [as a Muslim prophet], just as we believe in the prophet Muhammad."
[ame=http://www.youtube.com/watch?v=OQC0zeQFgJc]Jesus misrepresented as "Palestinian" by Mufti of the Palestinian Authority - YouTube[/ame]
 
Possible new pancreatic drug shows promise...
:clap2:
Pancreatic cancer: Trial drug MRK003 shows promise
20 February 2012 - Doctors want to improve the prognosis of this aggressive cancer
Scientists say they may have found a new weapon against pancreatic cancer after promising early trial results of an experimental drug combination. Giving the chemotherapy agent gemcitabine with an experimental drug called MRK003 sets off a chain of events that ultimately kills cancer cells, studies in mice show. Patients are now testing the treatment to see if it will work for them. The Cancer Research UK-funded trials are being carried out in Cambridge.

Father-of-two Richard Griffiths, 41, from Coventry, has been on the trial since being diagnosed with pancreatic cancer in May 2011. "After six cycles of treatment, a scan showed the tumours had reduced and so I have continued with the treatment," he said. "The trial gives you hope - I really feel I can do this with the science behind me."
Aggressive cancer

Cancer Research UK says it is prioritising research into pancreatic cancer because the survival rate still remains dismally low. About 8,000 people in the UK are diagnosed with pancreatic cancer each year, and the disease is the fifth most common cause of cancer death in the UK. Survival rates are very low in relation to other cancers, and the length of time between diagnosis and death is typically short, usually less than six months. The most recent data for England show that about 16% of patients survive the disease beyond 12 months after diagnosis - prompting the need for new treatments.

Professor Duncan Jodrell, who is leading the trials at the University of Cambridge, said: "We're delighted that the results of this important research are now being evaluated in a clinical trial, to test whether this might be a new treatment approach for patients with pancreatic cancer, although it will be some time before we're able to say how successful this will be in patients." In total, about 60 patients with advanced pancreatic cancer will be recruited for the first Phase I/II clinical trial.

BBC News - Pancreatic cancer: Trial drug MRK003 shows promise
 
And what have the Palestinians contributed to humanity?

Simulated_Dynamite_Suicide_Vest.jpg
 
It is not an artificial pancreas. It is merely an insulin pump and a subcutaneous glucose sensor and a program to monitor glucose levels and adjust with insulin injections with the pump.
 
warren buffett: "if you go to the middle east looking for oil, you don't need to stop in israel. But, if you're looking for brains, for energy, for integrity, for imagination, it's the only stop you need to make"

The Artificial Pancreas in Action: Must See Video | A Sweet Life

israeli-developed 'artificial pancreas’ tested
apparently for the first time in the world, a recent research study on children with type 1 (insulin-dependent, juvenile- onset) diabetes aimed at creating an effective artificial pancreas to produce insulin was held not in a hospital but in a hotel.

The clinical trial was conducted by specialists at the schneider children’s medical center (scmc) at the kibbutz ma’aleh hahamisha hotel outside jerusalem. The prospective, crossover study, in which the whole group receive the treatment but at different times, was part of the three-day dream (diabetes wireless artificial pancreas consortium) camp for children with diabetes.

It consisted of 18 kids aged 12 to 15 years; nine of them were were connected to the artificial pancreas system on the first night of the camp, while eight were connected on the second night. The benefit of being in a hotel rather than a hospital ward was that the more pleasant, non-threatening environment made the results more accurate.

The md-logic artificial pancreas, developed at the scms’s institute for endocrinology and diabetes, consists of an off-the-shelf subcutaneous glucose sensor that monitors glucose levels, and an insulin pump. The sensor and pump are connected to a computer that programs the information and stipulates the amount of insulin that should be released to the body in order to maintain blood glucose balance.

This innovation “closes the loop” between the sensor and the pump and relieves the patients with diabetes from the daily burden of dealing with their diabetes and has the potential to significantly improve the quality of life of patients with diabetes.

The experimental artificial pancreas is aimed at providing a real solution for patients with type 1 diabetes, which usually begins in early childhood. The research is being carried out at the shaffer institute for endocrinology and diabetes at the petah tikva hospital’s national center of childhood diabetes. The project is headed by institute director prof. Moshe phillip and dr. Revital.

Following the successful trial, phillip said: “i am proud to head and be a part of the pioneering team working for a number of years to find a technological solution that will significantly improve the lives of millions of diabetics around the world. The md-logic artificial pancreas and the dream projects will enable patients to be relieved of the continuous need to check glucose levels and inject insulin, while ensuring long-term balance which significantly reduces the chance of complications from diabetes. The entire staff in the institute is excited to be part of this important historic project.”

“this is a significant landmark in research,” he added. “this is, to the best of our knowledge, the first time in the world that such a trial project has been taken outside the hospital, illustrating a normal life for youngsters with diabetes, while using an automatic insulin delivery system during the night.” the overall success of the research represents genuine good news to millions of patients with diabetes in israel and the world, he said.

Con't: israeli-developed 'artificial pancrea... Jpost - health & science
fantastic!!!!!!
 
It is not an artificial pancreas. It is merely an insulin pump and a subcutaneous glucose sensor and a program to monitor glucose levels and adjust with insulin injections with the pump.

And guess what? That's exactly what a pancreas does with insulin levels in the blood.
 
Possible pancreatic cancer cure breakthrough...
:clap2:
Potential Breakthrough in Pancreatic Cancer Treatment Reported
March 20, 2012 - Overall survival increases by 70% in mice
Scientists in Seattle are reporting a potential breakthrough in the treatment of pancreatic cancer, a disease which stubbornly resists most therapies. Pancreatic cancer tumors are resistent to chemotherapy partly because they form a biological barrier around themselves. Researchers at the Fred Hutchinson Cancer Research Center believe they've found a way to break that barrier down. "Pancreatic cancer actually has the highest one-year and five-year mortalities of any cancer," says Sunil Hingorani, senior author of the study published in Cancer Cell.

That high fatality rate has been something of a puzzle for researchers who study pancreatic cancer. Powerful chemotherapy drugs that kill off pancreatic cancer cells in the laboratory are next to useless in living cancer patients. Scientists have observed how tumors in the pancreas, in effect, wall themselves off with a collagen material similar to scar tissue. That exerts pressure on the blood vessels that supply the tumor, collapsing many of them and restricting not just the flow of blood but also of chemotherapy drugs. "And so in this way, the tumor actually isolates itself completely from the circulation, and when we try to give drugs through the vein, they essentially bypass the tumor and instead go everywhere else," Hingorani says.

So the problem may not be that the chemotherapy medicine doesn't work, but that it simply may not be able to reach its target. To find out, Hingorani and his colleagues used mice genetically engineered to stand in for human pancreatic cancer patients. They treated them with the standard chemotherapy drug, gemcitabine, plus the enzyme PEGPH20, which is designed to open up the collapsed blood vessels that supply the tumor. "We found that in essentially every animal that we tested, we saw the tumors shrink or at least stop growing," he said. "And we found that overall survival increased by about 70 percent — so not quite doubling, but just about."

Of course, what works on mice doesn't necessarily work on people, so the researchers are beginning human trials. Hingorani says he is optimistic, but cautions that it will be a year or two before results are available from the tests with people. However, if all works as the researchers hope, not only would the chemotherapy be more effective, there may be fewer nasty side effects. That's because with more of the medicine actually reaching the tumor, doctors may be able to use less of the powerful chemotherapy drugs.

Source
 

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