Europoean e.Coli Engineered to Kill?

[JBeukema]

So how, exactly, does a bacterial strain come into existence that's resistant to over a dozen antibiotics in eight different drug classes and features two deadly gene mutations plus ESBL enzyme capabilities?

There's really only one way this happens (and only one way) -- you have to expose this strain of e.coli to all eight classes of antibiotics drugs. Usually this isn't done at the same time, of course: You first expose it to penicillin and find the surviving colonies which are resistant to penicillin. You then take those surviving colonies and expose them to tetracycline. The surviving colonies are now resistant to both penicillin and tetracycline. You then expose them to a sulfa drug and collect the surviving colonies from that, and so on. It is a process of genetic selection done in a laboratory with a desired outcome. This is essentially how some bioweapons are engineered by the U.S. Army in its laboratory facility in Ft. Detrick, Maryland

Forensic evidence emerges that European e.coli superbug was bioengineered to produce human fatalities