Capital Dumbing Down: Legislator's Pedophilia

Amorphous aluminosilicates have been found at the core of senile plaques in Alzheimer's disease, and aluminum has been detected in neurons bearing neurofibrillary tangles -- both in Alzheimer's disease and in the Parkinson's disease with dementia that is prevalent on Guam and other Pacific areas.'
(Birchall and Chappell, The Chemistry of Aluminum and Silicon in Relation to Alzheimer's Disease, Clin. Chem. 34: 265-7 [1988])

'Further controversy ensued with the demonstration of aluminum toxicity in dialysis dementia and reports of NFT-bearing hippocampal neurons in the amyotrophic lateral sclerosis-Parkinsonism complex (ALS/PD) of the Pacific basin rim.'
(Jacobs RW et al, A Reexamination of Aluminum in Alzheimer's Disease: Analysis by Energy Dispersive X-Ray Microprobe and Flameless Atomic Absorption Spectrophotometry, Canadian Journal of Neurological Sciences (1989) 16:498-503)

Even with such sophisticated equipment, Jacob's et al's study is questioned due to Washington State as having the highest Alzheimer's percentage (43%) of all U.S. states. This is also the state for mad cow prions at Mabton.
 
Washington Tops U.S. in 12-Year Alzheimer's Death Rates
socialcapitalreview.org/washington-tops-u-s-in-12-year-alzheimers-death-rates/
 
Even prion maps for CWD in Wisconsin are more detailed than Alzheimer's maps or aluminum maps for Wisconsin. For the latest study by world aluminum experts, Exley et al's 2018 article analyzes the aspartate protein, which is mutated frequently in influenza viruses, thus linking to the virus entry point, the ethmoid sinus in avians, humans, etc. and the aluminosilicate hypothesis.

''In addition, we also provide Table 3, the thermodynamics of relevant structures found in our previous works, with similar quantum methods. For instance, in the case of the experimentally and theoretically studied GEGEGSGG ocatpeptide we obtain different delta-G values depending on the coordination of aluminum. We have chosen three paradigmatic cases: i)Ni-GEGEGSGG where aluminum interacts with only one aspartate sidechain (delta-G = -33.7 kcal/mol), N6-GEGEGSGG which shows one aspartate sidechain in the first coordination shell and a second carboxylate group in the second coordination sphere (delta-G = -67.9 kcal/mol) and finally, P1-GEGEGSGG with a phosphorylated serine coordinating aluminum (delta-G[aqeous] = -789.2 kcal/mol). All cases show a more favorable interaction than with the models in which aluminum is directly interacting with the peptide backbone.'

This also introduces the phosphorus which links to fluorine in fungal nerve toxins (Trichoderma) and the serine indeed links to Guam and the amyotrophic lateral sclerosis (ALS)/Parkinsonism stats for that island, which is high in aluminum. There may be a German ALS family in Wisconsin which would be a founder-effect family in that state. Further investigation is warranted, though this 2017 Tokyo study links prions to the serine for ALS:

De Novo Design of RNA-Binding Proteins with a Prion-Like Domain Related to ALS/FTD Proteinopathies
De novo design of RNA-binding proteins with a prion-like domain related to ALS/FTD proteinopathies. - PubMed - NCBI
 
Aluminum Poisoning (Dr. Pepi)
www.drpepi.com/aluminum-poisoning.pfp
'Just one slice of individually wrapped processed cheese can contain up to 50mg aluminum.'

What Foods Contain Harmful Aluminum?
What Foods Contain Harmful Aluminum?
"Generally Recognized as Safe" (GRAS): aluminum ammonium sulfate, aluminum potassium sulfate, aluminum calcium silicate, aluminum nicotinate, aluminum potassium sulfate, aluminum sodium sulfate, aluminum stearate, sodium aluminum phosphate, and aluminum sulfate....FDA does not require that aluminum should be listed as an ingredient.'

Asparagine and aspartic acid differ from each other by one hydrogen atom. For exley's aspartate-aluminum study (above), chronic wasting disease in deer (which prions can be vectored by crows) links to this CWD study which gives some clues as to why fallow deer may not be susceptible to CWD:

'We extracted DNA from liver specimens from 23 fallow deer, and the open reading frame of the PRNP gene was amplified and sequenced....sequences were identical to that reported in GenbBank accession AY286007 except for a single synonymous change (aac/aat, encoding asparagine) at codon 138.'
(Rhyan JC, et al, Failure of Fallow Deer (Dama dama) to Develop Chronic Wasting Disease When Exposed to a Contaminated Environment and Infected Mule Deer (Odocoileus hemionus), J. Wildl. Dis. [2011] 47:739-44)
 
The ALS (amyotrophic lateral sclerosis) connection to Wisconsin has been found and is now being investigated due to neurological susceptibilities of the gene to environmental insults such as aluminum. This will link to Guam (high aluminum) and the ALS/Parkinson's connection to the Pacific Rim.
 
I see that you have a lot of interest in it, but your style of posting about it isn't going to garner much attention here.
 
Besides the cynicism, we've been aware of the autistic parameter for some time now.

Cheers,
Badger2
 

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