Cannabis Chemical for Pancreatic Cancer

[badger2]

3 hours ago.
https://www.yahoo.com/lifestyle/stu...impact-harvard-researcher-says-165116708.html
'....flavonoid FBL-03G.'

This is suspicious, Chinese have done the same thing with reports on natural compounds by naming it with a number. This is very likely not a newly discovered compound, but its identity hides behind a number so that those who are clued up about such chemistry can't verify their suspicions.

 

[badger2]

This is the original Pubmed report:
Jul 2019
Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer. - PubMed - NCBI
' a natural isomer of cannaflavin B.'

1985 Discovery of Cannaflavin
Isolation from Cannabis sativa L. of cannflavin--a novel inhibitor of prostaglandin production. - PubMed - NCBI
'....a prostaglandin inhibitor....'

 

[badger2]

Handbook of Natural Flavonoids shows the structure of cannaflavin B, C21H20O6, 5,7,4'-Trihydroxy-3'-methoxy-6-prenylflavone, from Cannabis sativa (Cannabidaceae), Barrett, ML, Experentia, 1986 42: 452. We see a geranyl moiety in cannaflavin A, which is reminiscent of it anti-mycobaterial properties, A differing from B only in having a longer side chain.

 

[CrusaderFrank]

3 hours ago.
https://www.yahoo.com/lifestyle/stu...impact-harvard-researcher-says-165116708.html
'....flavonoid FBL-03G.'

This is suspicious, Chinese have done the same thing with reports on natural compounds by naming it with a number. This is very likely not a newly discovered compound, but its identity hides behind a number so that those who are clued up about such chemistry can't verify their suspicions.

The Israelis have been researching cannabis for 40 years

 

[CrusaderFrank]

I recently baked the most heavenly brownies by decarboxilating 5 g of gelato for about an hour and a half lowest over setting then added the mix to a stick of melted Kerry's Gold butter and 1 cup of water and let that simmer over very low flame for 5 hours, turning the flame off about every hour or so for about 1/2 hour. Once strained I added in Gelato terpene, pinene a and b terpenes and CBD oil to the butter

 

[airplanemechanic]

I recently baked the most heavenly brownies by decarboxilating 5 g of gelato for about an hour and a half lowest over setting then added the mix to a stick of melted Kerry's Gold butter and 1 cup of water and let that simmer over very low flame for 5 hours, turning the flame off about every hour or so for about 1/2 hour. Once strained I added in Gelato terpene, pinene a and b terpenes and CBD oil to the butter

I had no idea making pot brownies was so complicated.

 

[badger2]

Hell, #5's decarboxylations are happening all the time. Note this prenyl moiety, morphing with a terpene, in concert! :

May 2019 Decarboxylation of Terpenes
The UbiX flavin prenyltransferase reaction mechanism resembles class I terpene cyclase chemistry. - PubMed - NCBI
'...UbiX flavin prenyltransferase....in concert to decarboxylate alpha-beta unsaturated....prenylated FMN....a class I terpene cyclase reaction....'

 

[RoshawnMarkwees]

There’s an available rent-free tent on an LA street with y’all’s names on it.

 

[CrusaderFrank]

I recently baked the most heavenly brownies by decarboxilating 5 g of gelato for about an hour and a half lowest over setting then added the mix to a stick of melted Kerry's Gold butter and 1 cup of water and let that simmer over very low flame for 5 hours, turning the flame off about every hour or so for about 1/2 hour. Once strained I added in Gelato terpene, pinene a and b terpenes and CBD oil to the butter

I had no idea making pot brownies was so complicated.

It's trial and error. My sister in law, raised by Seattle hippies, raved about the latest batch.

 

[badger2]

The tent could be a base of operations, yes.

2015 Russia
[At the origin of the development of russian angiology (dedicated to the 150 birthday of academician N.P. Kravkov)]. - PubMed - NCBI
'....on isolated animal organs (heart, kidney, spleen, pancreas)....organs of cadavers of people who died of various diseases: tuberculosis, typhoid fever and epidemic typhus....'

2014 India
Pancreatitis in scrub typhus. - PubMed - NCBI

 

[Vallie4]

I recently baked the most heavenly brownies by decarboxilating 5 g of gelato for about an hour and a half lowest over setting then added the mix to a stick of melted Kerry's Gold butter and 1 cup of water and let that simmer over very low flame for 5 hours, turning the flame off about every hour or so for about 1/2 hour. Once strained I added in Gelato terpene, pinene a and b terpenes and CBD oil to the butter

It's trial and error. My sister in law, raised by Seattle hippies, raved about the latest batch.

 

[Shawnee_b]

. Once strained I added in Gelato terpene, pinene a and b terpenes and CBD oil to the butter

Stop swearing at us!